Sentence examples for mutation was shown from inspiring English sources

The PDHX variant was tested by Sanger sequencing, and the mutation was shown to be co-segregating within the family.

This mutation was shown to be responsible for the improvement in fermentation using KJΔgalP as the host and expression vectors with native galP and with mutant galP∗.

Moreover, a channel created to the heme pocket by removal of the native His64 gate (His64 to Ala64 mutation) was shown to facilitate the binding of substrate, resulting in enhanced catalytic efficiency for the triple mutant L29H/F43H/H64A Mb, which is beyond the addition of both double mutants, L29H/H64A Mb and F43H/H64A Mb.

This mutation was shown to reduce the serum half-life of the scFv-Fc fragment from 10 days to 27 h by preventing the interaction of the intact Fc region with the Brambell receptor (FcRN) responsible for diverting antibodies away from the degradation pathway in cellular lysosomes (Figure 1a). Figure 1 A chimeric intact antibody and single-chain Fv-Fc (scFv-Fc) fragment.

In accord with this hypothesis, the His170Ala mutation was shown to dramatically impair the CRT chaperone function in vivo [15].

While the ropB mutation was shown to have no effect on hemolysis of RBC's, extracellular DNase activity or survival in the presence of neutrophils, strains with the mutated ropB allele were less virulent in murine systemic models of infection.

The mutation is shown in Fig. 5.

A typical max min mutation is shown in Fig. 6.

The results of UV mutation are shown in Table 1.

S306F was observed in all 33 clones except one, and the mutation is shown to stabilize the enzyme toward denaturation.

The measured prevalence of this mutation is shown in Figure 5.