Sentence examples for mutation was primarily from inspiring English sources

However in our analysis, the N163H/K/T mutation was primarily observed in isolates with reduced zanamivir sensitivity, which seems to indicate an opposite effect of mutation involving N163.

Interestingly, the p. (Phe508del) mutation was primarily prevalent among patients living in Gaza (68%) as compared to patients in the West Bank (32%).

A proportion (20 30%) of lung cancer patients with EGFR mutation is primarily resistant to EGFR TKIs.

Crossing with A. halleri and transgenic data have shown that an SCR mutation is primarily responsible for self-compatibility according to this prediction.

The SBDS proinvolved in RNA metabolism and ribosome-associated functions, but SBDS mutation is primarily linked to a defect in polymorphonuclear leukocytes unable to orient correctly in a spatial gradient of chemoattractants.

Although more than half the variants described are single amino acid substitutions that may lead to the translation of mutated protein with altered function, there is reasonable expectation that the functional effects of heterozygous mutation are primarily due to haplo-insufficiency (Table I).

The mutations were primarily deletions, missing bits of code, that rendered proteins kaput.

In vitro and in vivo studies reveal that resistance mutations are primarily found within the region spanning amino acid 36 45 of gp41.

The hMre11 structure in conjunction with biochemical analyses reveals that many tumorigenic mutations are primarily associated with Nbs1 binding and partly with nuclease activities, providing a framework for understanding how mutations inactivate Mre11.

Pathogenic mutations are primarily found in the enzymatic domains of LRRK2, the GTPase and the kinase domain.

The contribution of the non-hydrophobic residues needs further analysis as it is unclear whether the effect observed from the double/triple non-hydrophobic-residue to alanine mutations is primarily due to an increase in overall hydrophobicity or to the loss of the specific polar side-chains.