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Y105E, a phosphorylation-mimic mutation, was previously reported to inhibit PKM2 activity.
The single recessive z3 mutation was previously mapped onto the classical genetic map of the short arm of chromosome 3 (Iwata et al. 1979).
This mutation was previously associated with inherited cardiomyopathy [25], [26].
A chromosome carrying the spinosad resistance gene mutation was previously identified using AFLP markers [15].
A broad G+C substitution mutation was previously described to test the functional importance of ARS elements [24].
This mutation was previously characterized by a low microsatellite instability phenotype [27], and a lack of functional defects, such as defective heterodimerization or ATP hydrolysis [28].
Similar(15)
Thirty-one families had mutations in KRT6A and of the 18 different mutations, four, including a nonsense mutation, were previously unreported.
Four of the six cases with C9ORF72 mutation were previously classified as FTLD-TDP type A while two cases had type B pathology.
The apparent overrepresentation of tRNA and nonsynonymous mutations among recurrent mutations was previously observed [52] for the worldwide mtDNA phylogeny (Table 2).
This mutations was previously reported in a study of Japanese adults [ 24], and.
None of these point mutations was previously described and only 11 of the 32 genes were known to be mutated in other cancers.
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