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Exact(29)
The mutation was predicted to be damaging by at least 5 in silico predictors.
Interestingly, BRAF V600E mutation was predicted to form a neoantigen when presented by HLA-A0301 or HLA-A1101 HLA-A1101
This missense mutation was predicted to be pathogenic according to the in silico programs SIFT: 0, Polyphen-2: 0.883, and MutationTaster: 0.97471.
The mutation was predicted to remove an AvaI site.
Bioinformatics analysis indicated that the p. K23N mutation was predicted to be disease causing.
This mutation was predicted to be probably damaging with a score of 1.00 by PolyPhen-2.
Similar(31)
Among them, the W51F mutation is predicted to be the most effective in increasing the oxidation potential of the protein.
In addition, the mutation is predicted to cause an alteration in the second structure, which impairs protein synthesis and enlarges sensitivity to aminoglycoside ototoxicity (Prezant et al., 1993).
p.R149C (g.940C>T) mutation is predicted to destabilize the protein in both models.
By analogy to previous studies using mouse orthologs, this mutation is predicted to abolish kinase activity.
For Omp31, the point mutation is predicted to lead to a truncation in the protein.
More suggestions(15)
mutant was predicted
transfer was predicted
evolution was predicted
mutation was described
mutation was detected
mutation was labeled
mutation was confirmed
mutation was repeated
mutation was genotyped
mutation was created
mutation was backcrossed
mutation was introduced
mutation was termed
mutation was found
mutation was named
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