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A VHL gene intragenic mutation was noted in 21 cases (45.6%), including 1 case with a biallelic mutation (case n°38, Table 4).
Moreover, a VHL gene mutation was noted in 1 of the 6 non informative ccRCCs (case n° 42, Table 4), and in case n°52, not available for LOH analysis because of the absence of normal tissue specimen.
While previously noted inter-strain differences were confirmed for different manifestations of caring behavior, self-maintenance and neglecting behaviors as well as the pup retrieval test, no strain-independent effect of the GR mutation was noted.
KRAS mutation status was evaluated in 205 patients, and mutation was noted in 88 of those patients (42.9%).
By week 48 in ARTEMIS, patients experiencing viral rebound had not developed any IAS-USA PI resistance mutations, 31 although one NRTI mutation was noted, M184V.
KRAS mutation status was evaluated in 205 patients and mutation was noted in 88 of those patients (42.9%), in concordance with the mutation rate of KRAS in CRC (35%to42%2%) [ 19].
Similar(53)
Those which appear to contribute some insight into pathogenic mechanisms (cobblestone malformation, GPR56 mutation) are noted above.
Because p53 mutation is noted in C33A cells but not in HeLa cells, the association between p53 mutation and galectin-1 promotor hypermethylation is worth investigating.
For the T[5-Me,8]G cross-link, a similar pattern of mutations was noted, but the mutational frequency was significantly higher than that of G[8,5-Me]T.
For the T[5-Me,8]G cross-link, altheugh the mutational frequency increased, a similar pattern of mutations was noted.
It is interesting to note that while, on the top strand, the G residues at the first position of the GYW or the second position of the RGYW motifs were significantly more mutated in NBS patients, no alteration in the rate of mutations was noted in the corresponding C residues at the reverse complementary motifs (WRC or WRCY; Table 2, Fig. 2 and Table S3).
More suggestions(15)
transfer was noted
mutation was described
mutation was detected
mutation was repeated
mutation was labeled
mutation was confirmed
mutation was genotyped
mutation was created
mutation was backcrossed
mutation was introduced
mutation was expected
mutation was termed
mutation was found
mutation was named
mutation was identified
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