Sentence examples for mutation was needed from inspiring English sources

For definitive diagnosis, however, an RB1 mutation was needed, but heterozygous promoter→exon 11 deletion was the only RB1 mutation detected in the primary tumor.

Especially, Galton posited that the ever-present individual variation that Darwin relied on could not be the source for evolution, because under blending inheritance which is due to sex the individual makeup could not persist; and thus a special, sudden mutation was needed, whose character would not be lost in the passage from one generation to the next [ 246, 247].

To figure out its significance, data from hundreds of thousands of patients — the world's collected data — on that mutation are needed.

Therefore, further analysis to elucidate the role of 83-position mutation is needed for understanding the fluoroquinolone resistance mechanism (Fig. 3).

Like humans, only one copy of the mutation is needed to cause this severe disease and no individuals have two copies of the mutation because it causes death of the developing embryo.

Further study for delineation of the deafness and KIT mutation is needed in the future.

If the new mutation is needed after transformation and before loopout, place the cut site toward far end of gene.

New method of functional analyses of AGC2 mutation is needed to provide more insight into SLC25A13 variants.

If only one mutation is needed, the resulting PCR fragments can be digested with specific restriction endonucleases and directly ligated with vector for subsequent subcloning.

Prospective randomised controlled trials examining the various interventions in relation to the woman's age and type of mutation are needed.

Interestingly, the different bacteria tested here readily proliferated on inhibition of PG precursor synthesis, strongly suggesting that no ispA-like mutation is needed to promote L-form proliferation.