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IDH1 hotspot mutation was more prevalent in the hypermethylated MS1 group (6 of 11 mutated cases), however, not reaching significance.
Another mutation was more recently reported to increase fetal microcephaly in a mouse model12.
In K-ras, G --> T transversion mutation was more frequent in the tumors from Egypt than from the US (58.6 vs. 26.9%), whereas G --> C transversion was detected in 26.9% of US tumors but none from Egypt (p = 0.003).
Within carrier families, the G84E mutation was more common in men with a diagnosis of prostate cancer (194 of 382, 51 %) than those without (42 of 137, 30 %), P = 9.9 × 10 -8) [odds ratio 4.42 (95%% confidence interval 2.56-7.64)].
The 101L-moPrP mutation was more susceptible to conversion to PrPres in the CAA than the wild type 101P-moPrP.
When growth curves were analyzed, the effect of the btuE mutation was more evident in aerobic conditions (Fig. S2A B).
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Women with a BRCA1 mutation are more likely to develop these tumors than another type.
Medical experts said that those who carry that gene mutation are more likely than not to live disease-free.
The mutation has the opposite effect of the one found in Colombia: people with the mutation are more likely to retain sharp cognitive abilities well into their nineties.
Tabbies with the mutation are more often found in Europe, Dr. O'Brien said.
Cells with the TERT promoter mutation are more likely to up-regulate telomerase, which allows them to continue to grow despite very short telomeres.
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