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In most previous studies K-ras gene mutation was mainly assessed by PCR.
In this study, mutation was mainly adopted to improve the bacterial flora's growth and activity.
Taken together, these results indicated that the loss of function of the G64D mutation was mainly attributable to a large reduction in the quantity of the mature ZIP13 protein, rather than to a disruption in ZIP13's ability to form a complex due to a change in its biochemical characteristics.
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The IDH1 R132H mutation is mainly mutated in secondary GBMs (89.9%), and it is observed with low frequency in primary GBMs (15.3%).
However, the NRAS mutation is mainly found in LSCRC [ 29].
EGFR mutation is mainly observed among patients with adenocarcionoma, never-smokers, and Eastern Asian ethnicity.
This gene mutation is mainly related to the pancreatic intraepithelial neoplasia but rarely lead to invasive PDAC.
This implies that the higher force in the presence of the mutation is mainly caused by an increase in the proportion of myosin heads that are strongly bound to actin filaments rather than a change in the force developed by individual cross-bridges.
The under-prediction of BRCA2 mutations was mainly within this category of families (8.60 expected versus 12 observed).
The failure of indexed amplicon sequencing to detect the remaining 10%% of mutations was mainly due to low read depth and a uniform threshold for calling a mutation.
When information on family members was restricted to the second-degree relatives of the first screened individual, the under-prediction of BRCA1 mutations was mainly among families with at least three cases of breast cancer and at least one case of ovarian cancer (3.12 expected versus 6 observed).
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