Sentence examples for mutation was insufficient from inspiring English sources

Although point mutation was insufficient to remove the 5′-T constraint, directed evolution from the randomized library yielded repeat-1 mutants with unbiased targeting sites for 5′-bases.

They found that while effective for helping students overcome some misconceptions, the tutorial's treatment of mutation was insufficient, and that the module could more explicitly contrast key concepts with misconceptions.

The observation that the 3R mutant largely abolishes SRP recruitment suggests that shorter hydrophobic regions, such as those remaining on either side of the mutation, are insufficient for robust recruitment.

However, most existing methods for the detection of low-level DNA mutations are insufficient for clinical applications because of the high background of wild-type DNA.

In such instances, individual gene mutations are insufficient to cause the disease on their own [ 26].

Simple evolutionary accumulation of point mutations is insufficient to explain such uneven distribution of heterozygosity.

Thus, current procedures to detect only KRAS exon 2 mutations are insufficient for selecting appropriate patients.

However, the currently available data on somatic mutations is insufficient to examine other, subtler effects of the nucleotide context.

A particularly difficult task is to break strong PPI in which two monomers are interlocked through extensive interactions and side-chain mutations are insufficient.

Thus, current methods to detect KRAS exon 2 (codons 12 and 13) mutations are insufficient for selecting appropriate candidates for this therapy.

However, we did not observe any obvious modification of the E2F1-dsRNA phenotypes (data not shown), indicating that these particular Su z 2 point mutations are insufficient to modify these phenotypes.