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Two R118K mutants originated from successive years (2007 2008), which could indicate that this mutation was established in the wild virus population.
Phase of the variant and mutation was established for a subset of individuals.
The diagnosis of the A3243G mtDNA mutation was established with DNA testing of peripheral blood samples using previously described techniques.
In addition, multivariate analysis revealed that the presence of the V600E BRAF mutation was established as an independent prognostic factor for reduced PFS and OS.
Since haplogroups N1b1 and T stem from very different branches in the human mtDNA phylogeny it can be concluded that the 4917 mutation was established at least twice during human evolution.
A TaqMan single nucleotide polymorphisms (SNPs) assay for detecting the NA R292K oseltamivir-resistance mutation was established, with primers (forward: 5′-CAT GTT ACG GGR ARC GAA CAG G-3′, reverse: 5′-TGG TCT ATT TGA GCC CTG CC A-3′), and probes (K292: FAM5′-CAC ATG CAA GGA CAA-3′MGB; R292: VIC5′-CAC ATG CAG GGA CAA-3′MGB).
Similar(54)
The mutant individual is then sequenced and the identity of the mutation is established.
Primary cell cultures from an aggressive fibromatosis tumor harbouring a truncating APC mutation were established.
The inhibitory effect of intron 7 sequences on splicing of intron 6 and the lack of effect of oligonucleotides on the splicing of intron 6 in the absence of such sequences suggest that the inhibitory effect of the C-to-T mutation is established in cooperation with intron 7 sequences.
The presence of drug resistance mutations was established by sequencing the neuraminidase (NA) gene.
The prevalence of KRAS and BRAF mutations was established in 712 GC: 278 GC from the United Kingdom, 230 GC from Japan and 204 GC from Singapore.
More suggestions(15)
transfer was established
mutation was provided
mutation was tested
abnormality was established
mutation was ascertained
mutation was achieved
mutation was maintained
mutation was described
mutation was detected
mutation was repeated
mutation was confirmed
mutation was genotyped
mutation was introduced
mutation was named
mutation was identified
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