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The MTND6 mutation was eliminated from the mouse female germ line within four generations.
We specifically ensured that a bus-1 mutation was eliminated using PCR.
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As a consequence, cancer cells which have lost essential genes by a mutation are eliminated from the tumor population.
The cancer present at the time of biopsy may have progressed further, and may not harbour the same mutation because the cancer cells harbouring the earlier mutation were eliminated by the immune system in an early event of tumour development (Nakagawa et al, 1991).
In agreement with previous studies on this and similar DExD/H-box proteins, we found that the RNA-stimulated ATPase activity of both mutations was eliminated, while wild type RIG-I activity was robust (Yoneyama et al., 2004; Cordin et al., 2006).
Consequently, the flow field mutations were eliminated.
"This process generates genetic diversity and, through natural selection, undesirable combinations and mutations are eliminated from the population, promoting long-term survival of the species.
Kimura's neutral theory asserts that the majority of DNA sequence polymorphisms observed within a species has no effect on the fitness, because the majority of harmful mutations are eliminated from the population by negative selection.
A universal and powerful selection is at the translation level, in which adverse mutations are eliminated or selected against.
A majority of these novel mutations are eliminated soon after their arrival by genetic drift and selection.
The rate at which mutations are eliminated would permit estimation of the strength of selection against them.
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