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This mutation was designed to disrupt the CR2 C3d interaction, either directly through steric inhibition, or indirectly through disruption of a physiological dimer.
The PRH F32E mutation was designed to inhibit the binding of PRH to TLE1.
This switch mutation was designed to restore the bulk and hydrogen bonds observed between WT-FIH and WT-CTAD.
This mutation was designed to block catalysis while retaining hydrogen-bonding interactions of the amino acid side chain.
In each case, the mutation was designed to substitute the minimum number of nucleotides and to avoid creating or altering the binding sites of other known TFs.
The S119A mutation was designed to abolish the hydrogen bond to the carboxyl function of CBZ to decrease the stability of the binding mode and, thus, the overall binding affinity.
Similar(52)
In the grouping genetic algorithm, the initialization, crossover and mutation are designed according to our problem's characteristics.
In the AGCUK algorithm, noising selection and division absorption mutation are designed to keep a balance between selection pressure and population diversity.
For this specific problem, the fitness function, the algorithm of genetic selection, crossover and mutation are designed to ensure the diversity of kernel function and more selected chances of optimal individual in evolution process.
For simplifying the process of cell disruption and immobilization, the lysis genes of phage λ (S−RRz) with the S amber mutation were designed to introduce into the over-expression system of GLA.
Third, the mutation is designed to occur.
More suggestions(15)
move was designed
deployments was designed
mutation was described
mutation was detected
mutation were designed
mutation was confirmed
mutation was repeated
mutation was labeled
mutation was genotyped
mutation was created
mutation was backcrossed
mutation was expected
mutation was introduced
mutation was termed
mutation was found
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