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The E2-G60D mutation was an important determinant of CHIKV infectivity for both Ae. albopictus and Ae. aegypti, but only moderately modulated the effect of the E1-A226V mutatinn in Ae. albopictus.
ASXL1 mutation was an independent poor prognostic factor for survival.
Carrying A354V or C1277STOP mutation was an exclusion criterion for controls.
The second mutation was an alteration in nucleotides in 38603801 position (T>A) of reference sequence.
In many cases, the mutation was an early stop codon (Fig. 3).
Our data strongly suggest that the TP53 mutation was an early founder mutation that was inherited by all subsequent subpopulations.
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This subsequent mutation was a shock".
This mutation was a previously unreported substitution followed by an insertion at the aa536 hotspot of known mutations (L536indelGV).
Thus, bacA mutation was a candidate for incorporation into live attenuated vaccines.
In the multi-variate analysis, a KRAS mutation was a poor prognostic factor (hazard ratio = 2.6, 95 % CI 1.8 3.7).
The second BBS2 mutation was a nonsense mutation c.1932T>A (p.Y644X) in exon 16.
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