Sentence examples for mutation via a from inspiring English sources

One abstract contained a reference to a mutation via a dbSNP reference id (e.g. 'rs1234').

These data support the pathogenicity of the zfT70I mutation via a toxic gain of function mediated in part through an increased susceptibility to oxidative stress.

We introduced the reported V38R mutation, via a single point mutation, in the codon optimized ldh gene (for details see the Methods section).

Previous work found that the genotoxin cytarabine causes increased myeloid differentiation in bone marrow cells with a Ras mutation via a p53-dependent mechanism [ 39].

Identification of a predicted disease causing mutation via any NGS approach requires validation, particularly if the mutation is novel for this phenotype.

Once established in the airways, P. aeruginosa continuously adapts to the changing environment, in part through acquisition of beneficial mutations via a process termed pathoadaptation.

We inferred the unobserved mutations via a data augmentation procedure that exploits uniformization and is robust to model misspecification (Minin and Suchard, 2008; O'Brien et al., 2009).

Additional evidence could come from direct observations of conversions among mutation data in pedigrees or father son pairs: the YHRD describes 54 mutation events, and include one case where the combination 12,14 gives rise to 14,14 in a single event either a two-step mutation via slippage, or a conversion event [Budowle et al., 2005].

The trp5 –A149C mutation reverts via a CG → AT mutation, which is a hallmark of oxidative damage, as an 8-oxoG frequently mispairs with an A, leading to a CG → AT transversion.

They can make a great contribution to the formation of new genes by copying known genes and generating mutations via an RF shift in them.

We suppose that complete revealing of mutations via an RF shift in genes is possible by the integration of these two techniques.