Sentence examples for mutation towards the from inspiring English sources
These combined data also suggest that, in early infection, reversion solely due to replicative fitness is atypical (although specific sites outside of the regions studied here may have a different dynamic), and that, in chronic infection, mutation towards the consensus is a dynamic process involving sustained turnover between consensus and mutant forms.
Charged to alanine mutation towards the C-terminal DP-L41033 DP-L41104110) also had no effect on binding of CBD-YFP (data not shown).
Third, we suggest considering the problem from a different angle that while GC3-poor genes have less CpG sites than GC3-rich genes, they are more body-methylated because as methylation increases in the 5′→3′ direction, there is more chance for mC→T mutation towards the middle of the gene.
The single Loop 2 mutation is L188H which extends this cluster of mutations towards the C-terminus.
Mutations towards the preferred DUES in the DNA of the 'donor' cell may preferentially spread to other cells, by uptake and recombination, when the 'donor' cell dies.
Sequences carrying point mutations towards the least frequent nucleotide were generated from the best DUES construct using a three-step cohesive-end PCR process.
Within epitopes, immune escape mutations towards the subtype consensus occurred rapidly, but were transient in 4/6 cases, perhaps reflecting a changing balance of replicative fitness and immune potency.
Taken together, these results indicate that G5-SSR426 is a hotspot, which, based on its length, is able to bias but not restrict mutations towards the mucA gene.
On the other hand, this phenomenon may represent a possible source of mutations towards the development of cancer [ 47, 48].
Further sequencing analysis covering the full env region may provide more detailed information of the possible mutations towards the evolution of new quasispecies.
Finally, nonsense mutations towards the end of a protein coding region may lead to a minor truncation of the protein with subtle functional consequences (22).
