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It requires a second advantageous mutation to proceed to homozygosity.
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In Drosophila melanogaster, the imp-α2 gene is critical during oogenesis for ring canal assembly; specific mutations, which allow oogenesis to proceed normally, were found to block early embryonic mitosis.
For mutations boxed in bold this was previously shown to proceed by increasing or decreasing H-ras nanoclustering, respectively.
However, an antibody approach is not ideal to detect and to quantify protein modifications and mutations but there is hope that MS might elucidate how best to proceed.
One way to proceed is to identify known pathways that are enriched in genes carrying somatic mutations [ 1, 7].
So how to proceed?
He decided to proceed.
How, then, to proceed?
Norton to proceed.
How to proceed?
They decided to proceed.
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