Sentence examples for mutation to look from inspiring English sources

Knowing what mutation to look for can help simplify and speed up testing.

It means that in order for doctors to have tested for the mutated gene in Jolie, one of her relatives must have been tested for the mutation after already being diagnosed with cancer, so that doctors knew what specific BRCA1 mutation to look for in her relatives.

We therefore took advantage of having made a previously unavailable double null mutation to look at DV border formation in the wing.

The Erasmus team believes that more than 100 laboratories and perhaps 1,000 scientists around the world need to know the precise mutations to look for.

Even in influenza, one of the most studied pathogens in the world, scientists hardly know what mutations to look for, he says.

Single molecule PCR, though less high through-put, is free of PCR enzyme induced errors and may be a better option for exact quantification of mutation load, or to look at very small amounts of tissue.

Range or specific mutations can also be used to look for driver mutations in other PKs in equivalent positions (see later).

To elaborate on this problem, a common way to detect deleterious mutations in the secondary structure of RNAs is to look for mutations that may cause a conformational rearrangement to occur.

To look at mutation load by PCR cloning, DNA was extracted from sections of fresh-frozen colonic mucosa using a standard lysis buffer (50 m m Tris HCl pH 8.5, 1 m m EDTA, 0.5% Tween-20, 200 ng mL−1 proteinase K). 1 μL of DNA was used as template to amplify a 442 bp fragment containing the HVS-1 region of the mtDNA.

If there are no living family members who have had breast and/or ovarian cancer then it is possible to sequence the entire BRCA1 and BRCA2 genes to look for mutations and this blood test is available privately," he adds.

Breast Cancer Action is now among the plaintiffs in a case being considered by the Supreme Court that challenges the right of Myriad Genetics Inc. to patent genes to maintain a monopoly on a blood test used to look for mutations that greatly increase the risk of cancer.