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Exact(5)
For these experiments, we constructed double mutants carrying either a class 1 or 2 daf-2 mutation along with the eat-2 ad465 eat-2 ad465to induce DR. Class 1 and 2 daf-2 mutations were previously defined by toeinducenotypic severity [7].
Hence, in this case, a DNA repair complex acts via genomic instability and mutation to induce cell death.
When expressed in MPPs, Flt3-ITD collaborated with Runx1 mutation to induce high-penetrance aggressive leukemias that were exclusively of the myeloid phenotype.
In order to test how dfp1-r35 affects the progression of meiotic S phase (meiS phase), we used the temperature sensitive pat1-114 mutotinduce induce a synchronous meiosis.
In order to assess the effects of correlation structure in a controlled way, we introduced a differential co-expression network simulation strategy that incorporated realistic network structures such as scale-free and ER, and we used random mutation to induce differential co-expression.
Similar(55)
Probably the BCP mutation needs combination of other several mutations to induce hepatocarcinogenesis.
This is in keeping with the established tendency of Trp53 mutations to induce tumours with EMT-type histopathological features in transgenic mouse models [ 17].
While their exact role remains to be tested, the potential of these two independently identified mutations to induce phosphorylation site changes on PILSLRE kinase, suggest importance in tumor development.
If the phospho-tail were binding elsewhere on PTEN, we would not expect the A5 and D5 clustered mutations to induce distinct conformational effects that would result in differential alkaline phosphatase susceptibility of the tail phosphates.
Thus the T293N mutation appears to induce a greater reduction in block by tolbutamide than glibenclamide.
As a first step towards judging the importance of the exact dEndoA-BAR curvature in vivo, we made mutations designed to induce curvature changes.
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