Sentence examples for mutation to increase from inspiring English sources

These engineered proteins include both active site mutations and a dimer interface mutation to increase the stability and ADPase activity of the modified human nucleotidase.

Any individual plant that happens to carry a mutation coding for, for example, a slightly stronger insect-repellent chemical will be favored by natural selection, and we would expect the mutation to increase in frequency in the population.

To establish infection, viruses likely evolved to accumulate mutation to increase the number of shared miRNA response elements with supportive host factors and decrease the number shared with inhibitory host factors; this hypothesis deserves further investigation.

We expect deleterious biological influences such as sperm mutation to increase along with paternal age and thus reduce child outcomes, but there are many other environmental factors that are also related to paternal age and also affect child outcomes.

We report that optimal in planta cleavage requires the addition of an N-terminal nuclear localization signal and introduction of a point mutation to increase DNA cleavage activity.

Furthermore, hsd-1 mutation synergizes with akt-1 mutation to increase DAF-16/FoxO target gene expression, and DAF-16/FoxO target gene expression in hsd-1 akt-1 double mutants requires not only DAF-16/FoxO but also DAF-12 [ 34].

These findings are consistent with other published studies linking KRAS mutation to increased translation of cancer related proteins, and chromosome instability [ 17, 18].

Even a very slight advantage is sufficient to cause new beneficial mutations to increase in proportion over the span of many generations.

Different modes of natural selection, however, can cause the frequencies of particular nonsynonymous mutations to increase within a population [ 54].

Murine studies have demonstrated that null mutations in L1cam can interact with Sox10 mutations to increase the penetrance of aganglionosis and result in more severe pathology (206).

It may be necessary to select patients without such B-Raf mutations to increase the rate of clinical response to imatinib in patients with metastatic melanoma.