Sentence examples for mutation to enhance from inspiring English sources
Moreover, it adopts a randomly generated scale factor in the modified mutation to enhance its exploration capacity.
The GRLBD construct (residues 521 777) contained a phenylalanine F602S mutation to enhance solubility.
Transformations were made using the Rut-C30 strain including a mus 53∆ [ 18] mutation to enhance genome-targeted integration according to the standard protoplast-based protocol [ 19].
To this end, we introduced an L97D mutation to enhance the channel conductance and/or open probability and also performed single channel recordings in the presence and absence of Ca2+.
Therefore, strong reductions in the affinity of virus-NPC1 recognition are predicted to reduce or eliminate infection in whole bat hosts, as observed in NPC1-deficient mice (Carette et al., 2011; Herbert et al., 2015), barring viral mutation to enhance this affinity.
We could rescue T cells responses against poorly immunogenic epitopes after introducing appropriate point mutations to enhance their interaction with MHC Class I molecules.
Because the structures reported by Chen, Harjes and Shandila all contain five mutations to enhance solubility of the protein [28], [31], [32], we first sought to determine whether these mutations alter the biological properties of A3G.
Multiple observations [21], [28] indicate the LRRK1 may not contain a bone fide WD40 domain, potentially contributing the failure of LRRK2 PD mutations to enhance the neurotoxicity of LRRK1 [22].
In line with this, while we showed that 3 nucleotide substitutions in NS5A coding sequence and 3'NTR were necessary and sufficient for adaptation of the genome-length domain III chimera to efficient replication in tamarins (Fig. 4, Table 1), we did not find these mutations to enhance genome translation or replication in the replicon model (Table 2, Fig. 5B).
These peptides can be subjected to mutations to enhance their natural anti-microbial properties in such a scenario.
Point mutations to enhance the solubility of the 7c12 monobody were made using Kunkel mutagenesis (Kunkel et al., 1991 ).
