Sentence examples for mutation thought to from inspiring English sources

It is remarkable that a mutator mutation, thought to be important when evolution is limited by mutation supply (de Visser et al. 1999) actually becomes common even in a large population where every single nucleotide mutation will occur nearly ten times every generation.

This isn't the first mutation thought to protect against malaria (sickle cell anemia does too, for instance), he says, but "this study is one of the most compelling because they have demonstrated a connection between genetics, NO production, and clinical status".

The other, ph2b, is a chemically induced mutation, thought to be a single nucleotide polymorphism (SNP) or a small insertion or deletion (INDEL) [ 22].

One mutation thought to be "true-positive" but not detected by Sanger sequencing was near the threshold line of our criteria.

The cycleave PCR technique was simultaneously applied to the detection of BRAF mutation, thought to be an adverse prognostic marker as well as a predictive marker for anti-EGFR therapy.

Genomic DNA was used to simultaneously amplify several gene loci using multiplex PCR, in order to capture and analyze 15 mutational hot spots enriched for, but not exclusive to, targets of mutations thought to arise early in leukemogenesis (Table 1).

More prevalent detected mutations, thought to contribute to antiretroviral resistance, were L63P (42%), L10I (35%), M36I (30%), V82A/T/F (26%).

For instance, a burst of mutagenesis concurrent with crisis and its attendant telomere dysfunction [20], [26] could contribute to the critical number of mutations thought to be necessary to elicit carcinogenesis [29], [30].

Especially important would be the analysis of AR mutations thought to be involved in prostate cancer treatment resistance [49] or AR mutations involved in the androgen resistance observed in AIS.

Mutations identified in ALS patients so far include truncation mutations thought to act through loss-of-function mechanisms and missense mutations [ 17, 45, 90, 135, 141, 191].

No mutations thought to be associated with artemisinin resistance have been detected in Cambodia, and no isolates resistant to artesunate in vitro have been found (12 ).