Sentence examples for mutation theory of from inspiring English sources

This led to the formal demonstration of defective MMR in this human hereditary disease and formed another persuasive validation of the somatic mutation theory of cancer32,33,34.

The "somatic mutation" theory of aging assumes that aging is due to the gradual accumulation of mutated cells that do not perform normally.

It became the basis of the mutation theory of evolution.

The somatic mutation theory of carcinogenesis and metastasis (SMT) is the currently prevailing concept of carcinogenesis.

The current prevailing theory of carcinogenesis is the somatic mutation theory of carcinogenesis and metastasis (SMT).

One chapter promotes the tissue organization field theory (TOFT) against the somatic mutation theory of cancer.

Epidemiologic analyses of timing of exposure in workers occupationally exposed to arylamines or in air-cured tobacco smokers suggest that arylamines exert both an early- and a late-stage activity, compatible with a two-mutation theory of bladder carcinogenesis.

There exists abundant evidence that mutations that change the function or expression of growth-regulatory genes can lead to progression to a cancerous phenotype, and the progressive accumulation of such changes as the underpinning of tumorigenesis forms the basis for the somatic mutation theory (SMT) of cancer [ 1].

The lack of a DNA mutation in the epithelial cells as a necessary initial event in carcinogenesis challenges the tenets of the somatic mutation-theory of carcinogenesis [ 23].

Assuming optimization in this scenario is achieved by higher expression of the original recessive mutation, theory predicts a net excess of male-biased genes (and/or deficit of female-biased genes) on the X.

(6) A different type of evidence sometimes cited in support of the somatic mutation theory is the observation that the incidence of some types of cancer increases rapidly with age.