Sentence examples for mutation the structure from inspiring English sources

Except for the sites of mutation, the structure is very similar to that of the native human IgG1 Fc, consistent with a heterodimer interaction kinetic KD of < 1 nM.

After mutation, the structure was subjected to optimization and energy-minimized using GROMACS force field.

Due to mutation, the structure became more rigid which is also supported by NH bond, density plot, PCA, and DSSP analysis.

From the molecular dynamics simulation analysis, we confirmed that due to occurrence of mutation the structure loss stability and became more flexible in conformation [ 74].

In order to study the structural consequences of the Jak3 mutations, the structure of the human Jak3 kinase and pseudokinase domains was modeled.

Mapping of the location of this mutation on the structure of MtbHadAB reveals that the mutation is located at the N-terminal end of αHD and lies at the bottom of the flavonoid binding pocket (Fig. 6C).

As expected, the disrupting point mutations almost completely abolished IRES activity, whereas the point mutation strengthening the structure had no significant effect (figure 6B).

The effects of redundancy on mutation, recombination, the structure of the landscape and the interplay between these ingredients are of particular interest.

We have examined the effect of this mutation on the structure and function of NCS-1.

Having shown that the R102Q mutation affected the structure of NCS-1 wexploreded the possibility that it might affect the Ca2+-binding characteristics of the protein.

To examine the effect of V145E mutation on the structure of leptin, we performed the molecular dynamics simulations on wild-type and mutant V145E leptin.