Sentence examples for mutation the risk from inspiring English sources

Different types of information were presented: absolute lifetime breast cancer risk for an average woman (i.e. population risk); breast cancer risk for women with BRCA1/BRCA2 mutation; the risk passing the mutated gene to children; and the women's personal breast cancer risk as based on her family history.

Where CRC were linked to somatic BRAF mutation, the risk was associated with long-term smoking [18].

For example, these annotations may describe the country of origin, the presence of a given resistance mutation, the risk group, the mode of transmission and so forth.

In breast cancer kindreds without a demonstrable BRCA mutation, the risk for breast cancer in female first degree relatives was about twice the risk in the general population.

Among women with a BRCA1 mutation, the risk of breast cancer increased by 1.2-fold for each first-degree relative with breast cancer before age 50 years (HR=1.21; 95% CI 0.94 1.57), and among women with a BRCA2 mutation, the risk of breast cancer increased by 1.7-fold for each first-degree relative with breast cancer (HR=1.65; 95% CI 1.00 2.71).

In genotype C virus infected patients, the BCP mutation is reported to accumulate as aging and associated with an increased risk of HCC, however, when the BCP mutation coexisted with precore mutation, the risk of HCC have decreased [ 33, 34].

While much is known about the three common Ashkenazi BRCA1 and BRCA2 mutations, the risk they confer varies.

The average American woman has a 12- to 13-percent risk of developing breast cancer, but for women with certain genetic mutations, the risk can range between 50 and 80percentt for breast cancer and between 20 and 50percentt for ovarian cancer.

Prof Turnbull said: "Our studies on stem cells does express a cautionary note that it might not be 100% efficient in preventing transmission, but for many women who carry these mutations the risk is far less than conceiving naturally". Mitochondria are tiny structures which sit outside the nucleus of the cell and convert food into useable energy.

With MLH1 mutations, the risk is 54%; with MSH2, 21%; and with MSH6, 16%.

Currently, as stated in the Justice Clarence Thomas' decision, The average American woman has a 12- to 13-percent risk of developing breast cancer, but for women with certain genetic mutations, the risk can range between 50 and 80percentt for breast cancer and between 20 and 50percentt for ovarian cancer.