Sentence examples for mutation the relative from inspiring English sources

Compared with men with no mutation, the relative survival rate at 5 years was only 48%.

The present study concerns the means by which polymerization is perturbed by mutation: the relative contribution of specific effects on the underlying structural mechanism and non-specific effects on protein stability.

As shown in Figure 2, in 14 out of 15 GISTs with a KIT mutation and in 2 out of 10 GISTs with a PDGFRA mutation, the relative expression of KIT was 1.47 arbitrary units (a.u).

Cancer dynamics depend on the rate of acquisition of fitness-conferring mutations, the relative selective advantage they give and the size of the susceptible cell population.

After excluding the families found to carry BRCA1 and BRCA2 mutations, the relative risk was estimated to be slightly lower but still elevated at 1.80 (95% CI: 1.38 2.35).

These results suggest that, as for the PS1 FAD mutations, the relative APL1β28 levels in CSF correlate with the relative generation of APL1β28 in the brain (R = 0.74, t = 4.10, p = 0.006; Fig 6B).

Interestingly, when the sequence logo is overlaid with the histogram of the corresponding mutation spectra, the relative frequencies of deleterious mutations and the average information are comparable.

The absolute fraction of αS bound as SL1 is significantly increased by the E46K mutation, while the relative abundance of binding modes SL1 and SL2 is increased by the A30P and A53T mutations (Table 1).

Functional testing of this allele in vivo and in vitro showed that the mutation perturbs the relative dosage of two PUF60 isoforms and, subsequently, the splicing efficiency of downstream PUF60 targets.

For example, tauopathies can be caused by an exon 10 mutation altering the relative expression levels of two isoforms (3R and 4R) of the MAPT gene [ 7, 8].

Finally, the effect of the inverting mutation on the relative amounts of low- and high-p Ka conformers in E. coli membranes was confirmed to exist in the natural halobacterial membranes.