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For an unlinked second-site mutation, the probability of cosegregation of G418 resistance and colony color or size in three tetrads is (1/6) or 0.005.
Since q ii is the probability that the variant doesn't change by mutation, the probability that it does is given by 1- q ii.
Consider an extension of the standard SMM model to arbitrary jump distributions, such that at each mutation the probability of a change of k repeats is q k (with q0 = 0).
However, because the youngest affected member of these families did not have a mutation the probability that she had a mutation would be very low and thus for interpreation the women labeled 'not tested' can be interpreted as being 'negative' [ 27].
Similar(56)
If both, sire and maternal grandsire are heterozygous for the p.W215X-mutation, the probability of the resulting calf being homozygous is 12.5%.
Because degenerative mutations greatly outnumber beneficial mutations the probability of neofunctionalization in small populations is rare whereas subfunctionalization is more likely to occur in these populations [ 33, 34].
For neutral mutations the probability of intra-individual fixation of the new variant was considered to be equal to its frequency in the heteroplasmic individual.
For non-neutral deleterious mutations the probability of intra-individual fixation was considered to vary between zero and the frequency in the heteroplasmic individual.
Even for selectively neutral mutations, the probability of ultimate fixation is only about one in 25 million for the large global yeast population.
As a result of the change of the selection parameters β i with the mutation bias, the probability that a mutation is accepted depends on the mutation bias.
To evaluate the impact of carrying a BRCA1 or BRCA2 mutation on the probability of experiencing premature natural menopause.
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