Suggestions(5)
Exact(6)
In 77 of these families negative for a BRCA1 or BRCA2 mutation, the frequency of MSH2 or MLH1 mutation was 2.6% and 0%, respectively.
Within the same group of patients who did not have an EGFR mutation, the frequency of ALK+ was 33% underscoring the importance of testing patients with this phenotype.
K- ras mutation: the frequency in superficial depressed adenomas was lower than that in polypoid adenomas (0% vs 31%: P = 0.018).
Since ACAs were also in our study more likely to exhibit an activating EGFR mutation, the frequency was overestimated in the Spanish study.
One caveat in our study is that all HPV- samples analyzed were also p16 negative, thus it remains possible that in HPV- samples with elevated p16 expression (for example, through RB1 mutation), the frequency of TP53 mutation is <100%.
APC mutation: the frequency in superficial depressed adenomas was lower than that in polypoid adenomas (7% vs 43%: P = 0.016), and that in polypoid carcinomas was similar to that in non-polypoid carcinomas.
Similar(54)
In the mutated cases, the mutation frequency ranged from 2.1 11.7%.
The LET value had a more striking effect on the mutation frequency in the M2 generation than the M1 generation.
We further examined the mutation frequency in the five gene sets across the 12 cancer types.
The mutation frequency of the hottest piece is 25 times higher than the average frequency of the testis.
Only in BRCA and LAML, the mutation frequency of the OCGs was significantly higher than that of the target genes.
More suggestions(15)
transfers the frequency
transfer the frequency
mutation the plasmid
mutation the deletion
mutation the solution
mutation the efficiency
mutation the spore
mutation the structure
mutation the power
mutation the crossover
mutation the story
mutation the message
mutation the feasibility
mutation the rest
mutation the patient
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com