Sentence examples for mutation the feasibility from inspiring English sources

After mutation, the feasibility of constraints (8) and (9) are evaluated.

All of the genes from the selected genes for Mutation 2 to the end must be checked against the feasibility, the so called feasible-gene checking, and repaired if necessary.

The aim of this study is to assess the feasibility of TaqMan Mutation Detection Assays (TMDA) based on castPCR technology to detect EGFR mutations in NSCLC clinical specimens and to compare this method with routine diagnostic techniques including direct sequencing and the EGFR Therascreen RGQ kit.

These data demonstrate the feasibility of BRAF mutation detection in cfDNA of patients with advanced melanoma.

To explore the feasibility to perform mutation analysis on single CTCs isolated with the DEPArray from CellSearch cartridges processed for standard CellSearch CTC enumeration, MDA-MB-231 cells were purified from a spiked blood sample pre-enriched with the CellSearch CTC kit.

This pilot study investigated the feasibility of detecting mutations in exons 5 8 of the p53 gene using single-stranded conformational polymorphism (SSCP) analysis in bladder-washing specimens from patients with bladder cancer.

We have previously reported the feasibility of detecting EGFR mutations in serum DNA using the Scorpion Amplification Refractory Mutation System (ARMS) method (Kimura et al, 2006).

We report on the basic analytical aspects of the system and provide proof-of-principle data showing the feasibility to perform both mutation and transcriptional analysis of single tumour cells or small groups of up to 10 tumour cells isolated with the DEPArray from immunomagnetically pre-enriched blood samples.

Taken together, our work demonstrates the feasibility of generating point mutations in mouse by base editing, and underscores the need to carefully optimize base editing systems in order to eliminate proximal-site deamination.

While change of H5 HA specificity is experimentally possible, the propensity for the requisite mutations to occur in vivo depends on the feasibility of the circulating strains of H5N1 virus acquiring the necessary nucleotide changes.

We demonstrated the feasibility of measuring EGFR mutations in plasma.