Sentence examples for mutation that transforms from inspiring English sources

Cbx 1 is a gain-of function mutation that transforms the posterior half of the wing (T2) into the posterior half of the haltere (T3).

For example, the additional driver mutation could be the mutation activating the KRAS/ BRAF pathway in a small colorectal adenoma, associated with the transformation from small to large adenoma, or the mutation that transforms benign adenoma into infiltrating carcinoma (Jones et al. 2008a).

This is why most tumors develop only following two causative hits: firstly a mutation that transform a cellular gene in an oncogene, and secondly, a mutation that inactivate a tumor suppressor [41].

The mutations that transformed TIR3 into a detector of sweet tastes must have happened over the last 42 million to 72 million years, allowing hummingbirds to evolve into a distinct family of nectar-drinking birds, they wrote.

Lewis showed that mutations that transform specific segments align on the genetic map in the order of the body segments that they affect (Lewis, 1978).

The generation of the first MM cell is a multistep process requiring a series of mutations that transform a normal plasma cell into an MM cell (Kuehl and Bergsagel, 2002; Bergsagel and Kuehl, 2005).

These mutations are known as 'drivers' and can be divided into two groups: (i) 'loss-of-function' mutations, which inactivate tumor suppressor genes (from here on 'inactivating mutations') and (ii) 'activating' or 'gain-of-function' mutations that transform proto-oncogenes into oncogenes.

Second, we use mutations that transform the mating system within C. elegans back to a dioecious system and demonstrate that the same hallmarks of sexual conflict as are observed within C. remanei can be recapitulated over a period of just a few dozens of generations of evolution in the presence of elevated male sexual encounters.

"We are not looking at a 'big bang' moment for the euro zone, a sudden mutation that would transform it into a completely different beast," the European Council president, Herman Van Rompuy, who is leading the exercise, said last week.

The genome rearrangement problem involves finding a series of mutations from a set of allowable mutation types that transform one genome into another.

A sequence from an S. invicta colony in Santiago del Estero, Argentina, carries a unique point mutation in exon 5 that transforms the stop codon (TAA) at position 154 into a glutamine-encoding codon (CAA), thereby extending the C-terminal tail of the resulting protein by 22 amino acids.