Sentence examples for mutation that overcomes from inspiring English sources

Within the kidney, Apc loss poorly initiates tumourigenesis and only provokes tumourigenesis when combined with a mutation that overcomes senescence.

The backward rate represents the rate of back mutation that overcomes single point mutations, the rate of insertion/deletion that reconstitutes a previous indel, the rate of excision of an IS, and the rate of gene conversion and lateral gene flow.

However, the researchers have discovered further genetic mutations that overcame this drawback to the drug-resistant strain.

We have isolated and characterized mutations that overcome the growth defect of Bacillus subtilis ccpA mutants lacking the major regulator of catabolite repression, in particular their glutamate auxotrophy.

But genetic mutations that overcome imprinting alone would have meant that Jesus only received X chromosomes, from Mary, making him a her.

In the third and central part of the article, we provide evidence that influenza evolves under a sufficiently high supply of beneficial mutations to trigger clonal interference: on average, more than one beneficial mutation that has overcome genetic drift is present in the population.

And about half those cases are caused by a particular mutation that can be overcome by sulfonylurea pills, an old and inexpensive class of diabetes drugs.

Using the nonviable prkaca site-directed mutants identified above, a genetic approach was employed to identify suppressor mutations that could overcome the non-viable phenotype.

Conversely, some CQR parasites (e.g. the FCB and Dd2 lines) appear to be well adapted to growth in vitro even in the absence of drug pressure, suggesting potential compensatory or adaptive mutations that can overcome the deleterious changes in drug resistant genes.

Our approach of deliberate horizontal transfer in the laboratory followed by experimental evolution offers an opportunity to identify both the limiting stresses and the mutations that can overcome these stresses.

The need for a very fit mutation (that causes a large antigenic change) to overcome a deleterious background also explains the punctuated nature of antigenic changes.