Sentence examples for mutation that may from inspiring English sources

In viruses resistant to protease inhibitors, the C in this downstream region is frequently mutated to U. At the protein level, this causes a Leu to Phe mutation that may increase cleavage efficiency and enhance the production of functional protease.

If these substitutions occur in germ cells, they constitute a heritable mutation that may eventually rise to polymorphic frequencies, hence resulting in a SNP that is methylation associated.

UMS reads a protein structure file (PDB file) and predicts the unfolding effect for a list of every possible missense mutation that may occur in the protein structure including an identity mutation.

The investigation was designed to study: (i) the clinical evolution of hyh mice; (ii) factors other than the α-SNAP mutation that may influence the expression of hydrocephalus; (iii) the neuropathological features underlying the different forms of clinical evolution.

Here we used pIg-tail expression system to construct a panel of eukaryotic cell-surface expression plasmids encoding the extracellular domain of gp41 with deletion of fusion peptide and/or introduction of L568P mutation that may disrupt the gp41 six-helix bundle core conformation as DNA vaccines for immunization of mice.

The present study reveals changes in the folding landscape of hPGK1 upon mutation that may affect protein folding efficiency and stability in vivo, also suggesting that native state stabilizers and protein homeostasis modulators may help to correct folding defects in hPGK1 deficiency.

We investigated the nuclear mutational profile of oncocytic tumors to pinpoint the mutations that may trigger the early oncogenic hit.

Interestingly, our patient had both BRAF and NRAS mutations that may be involved in the trans-differentiation process.

Both UVB and UVA rays damage the cells' DNA, potentially causing mutations that may lead to cancer.

Consequently, a selection of adaptive mutations that may account for the observed translation effects seems unlikely (Fig. 3d, e).

There are perhaps hundreds of genetic mutations that may slightly alter the brain's wiring as it develops.