Sentence examples for mutation that introduced from inspiring English sources

In contrast to the stability of the epitope tags, the SV40 NLS sequence was rapidly mutated by a frameshift mutation that introduced negatively charged amino acids into the basic NLS.

Most probably, both ORFs were generated as the result of a point mutation that introduced a stop codon in SARI_02719.

Members of two consanguineous families carried an insertion mutation that introduced an additional glycine residue at position 403 (403_404insGly) in the highly conserved, alternatively spliced region in domain I.

Sequence coverage was low and incomplete across lin-13 in sam12 worms, so we sequenced lin-13 and found a C to T mutation that introduced a stop codon (Q1585*).

We expected this protein to play a significant role during virus infection in mice because a mutation that introduced a novel AUG codon upstream of the authentic AUG 1 site and restored P78 protein expression in a mammalian cell culture infected by the AUG 1 KO mutant virus was selected (Supplementary Figures S1).

At codon 1956, we found a point mutation that introduces a premature stop codon, reducing the length of EAST protein from 2301 to 1955 amino acids.

In ePop, luxR* contains a frame-shift mutation that introduces an early stop codon and completely abolishes the luxR DNA-binding domain, as determined by homology to TraR [12].

A low magnitude of PFDs across 4 major SCOP classes confirmed the long-held myth of protein interior with low dielectric constant and explains why charge burial in the protein interior is so prohibitive and why a point mutation that introduces net charges or dipoles deep within the interior can destabilize the protein.

p53[11-1B-1] is a point mutation that introduces a stop codon at nucleotide residue 211, and is predicted to yield a 70AA truncated protein ("M").

Under mutation selection balance, the genetic variation observed in populations reflects an equilibrium between mutation that introduces deleterious variation and purifying selection that depletes it (reviewed by Johnson and Barton 2005).

The D27L, E34F, R37A superclamp mutation that introduces hydrophobic residues in the CpxI accessory helix did not change the ability to rescue the complexin I-III KO phenotype.