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Any random mutation that increased low-light vision would have conferred a distinct survival advantage for these animals.
This paradigm was used to screen for lines that displayed aberrant arousal behavior, discovering a dopamine receptor mutation that increased acute arousal but decreased night-time activity.
Thus, FBA predicts that the gltA1 mutation that increased CS flux improved the component of competitive fitness in the LTEE related to acetate utilization.
The gltA1 mutation that increased citrate synthase activity was beneficial to fitness when it evolved prior to the Cit+ innovation when only glucose and acetate could be utilized, as shown in the bar graph on the left.
However, there must be some additional effect of rps5 on UUG initiation since it was able to suppress UUG recognition in a yeast strain that harbored an eIF5 mutation that increased UUG initiation.
By comparison, mtDNA mutation that increased caloric utilization for ATP (thus decreasing energy lost to heat production) would be better adapted to low calorie diets and warmer climates (e.g., sub-Saharan Africa).
Similar(51)
— Sergey Brin, a Google co-founder, said Thursday that he has a gene mutation that increases his likelihood of contracting Parkinson's disease, a degenerative disorder of the central nervous system that can impair speech, movement and other functions.
If a cell acquires a mutation that increases the chances that its offspring will emigrate from the neoplasm, that clone should be at a disadvantage within the primary neoplasm, because some of its reproductive potential is lost to emigration [4].
In vitro, a mutation that increases antioxidant production may benefit BCG by reducing oxidative damage to cell wall lipids that otherwise would yield aldehydes and other metabolites that retard growth.
Indeed, a mutation that increases the negative charge of the CpxI accessory helix inhibits release and a mutation that decreases the negative charge enhances release.
An amplification is a mutation that increases the copy number of a specific DNA segment in a cancer cell [ 3, 4].
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Justyna Jupowicz-Kozak
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