Sentence examples for mutation that inactivates from inspiring English sources

A 'gene knockout' or 'knockout' is a mutation that inactivates a gene function.

Indeed, the B. anthracis chromosome is largely distinguished only by four integrated, non-inducible prophages [32] and a single nonsense mutation that inactivates plcR [33].

First, a mutation that inactivates the antiviral defense should result in flies that are unable to clear a low-titer infection.

Also, transgenic mice homozygous for a mutation that inactivates the IL-4 gene cannot produce IgE.

FUdR selects for bacteria harboring a plasmid with any mutation that inactivates the HSV- tk gene.

Such a synergistic increase in mutation rate was previously observed in a strain with pol2-4,C1089 double mutation that inactivates proofreading and alters the polymerase domain [ 30].

One prior study by Mistlberger et al. showed that genetically obese Zucker rats (containing a point mutation that inactivated the leptin receptor [37], [38], [39]) had enhanced FAA when kept on 22 days of RF with a 3 hr RF window [29].

Indeed, all of the tumors from patients who carried this particular T-to-A mutation also had additional mutations that inactivate the APC gene.

It turns out that all of the bird species share genetic mutations that inactivate genes involved in the formation of both tooth enamel and the portion of the tooth called dentin.

Since point mutations that inactivate the transcription termination function of GGT restore downstream promoter activity, the ability to block read-through transcription is the only property of GGT that is required for inhibition [21], [22].

Forward mutations that inactivate the HSV-tk protein are scored after transfection of E. coli and selective plating.