Alanine 206 of yeast enhanced Venus (yEVenus) was mutated to lysine (a mutation that has been shown to prevent dimerization of GFP and its variants [36]) by site-directed mutagenesis of pKT103 [37], yielding yeast enhanced monomeric Venus (yEmVenus).
The only single mutation that has been shown to increase HA stability is E47K.
Brown's son, Walker, was born with a genetic mutation that has deprived him of even the most rudimentary capacities.
This one and only Y has the same sequence of DNA units in every man alive except for the occasional mutation that has cropped up every thousand years so and is then inherited by all that individuals' descendants.
A New York Times photographer returned to several of the sites this year, capturing in some cases the kind of transformation and mutation that has been a constant in the life of the city, but in other cases showing how some spots have been strangely immune to change.
That's not a theoretical question for journalist Lizzie Stark's relatives, who grapple with the horrific legacy of cancer built into the family DNA, a BRCA mutation that has robbed most of her female relatives of breasts, ovaries, peace of mind, or life itself.
Ongoing studies at the Hereditary Gastrointestinal Cancer Registry in Hong Kong have revealed a unique germline MSH2 c.1452–1455delAATG mutation that has not been reported in other ethnic groups.
This one and only Y has the same sequence of DNA units in every man alive except for the occasional mutation that has cropped up every thousand years" (The New York Times, Nicholas Wade 5/27/03).
Initiation refers to genetic mutation that has the potential to result in unregulated cell growth.
Evolutionary biologist Ernst Mayr once argued that human intelligence is itself a lethal mutation that has put the species on a collision course with its own and possibly even the planet's extinction.
It is a hypomorphic mutation that has two amino acid substitutions in the extracellular domain of the receptor [46].
