Sentence examples for mutation that generated from inspiring English sources

One of the cDNA had a mutation that generated a premature stop codon, rendering it non-functional.

If CCD4 is confirmed to be the major factor responsible for carotenoid degradation, then the mutation that generated the RHB cultivar is likely to be a gain-of-function mutation, restoring ccd4 function.

The additional observation that various phenotypes must be acquired suggests multiple mutations with no clonal expansion or a mutator mutation (a mutation that generates more mutations) coupled with clonal expansion [ 41].

They can result from a genetic mutation that generates the harmful prion or from an infection of prions from an outside source, most likely in meat that is consumed -- or simply by chance: a certain number of proteins in the body just happen to lose their shape over time and bring about the disease.

At the same time, A at 3511 was changed to T, a silent mutation that generates a BglII site overlapping ry.

An analysis of the type of mutation that generates a protein truncated at codon 204 revealed interrupted synthesis at the first fibronectin type III-like domain.

These alleles include two null alleles: one lacking a 130-kb region harboring the entire gene (e1-nl) and the other having a single-base deletion that leads to a frameshift mutation that generates a premature stop codon (e1-fs).

The codon for Ser of rHtrA was mutated to alanine (rHtrASA) using the primer pair 5′-CATTAACCCTGGTAACTCTGGTGGTC-3′ and 5′-CACCAGCGTTACCCGGGTTAATGGCC-3′, which also introduce a silent point mutation that generates an additional SmaI restriction site.

ONYX-015 contains a 827 bp deletion in the E1B region of the viral genome and a point mutation that generates a premature stop codon preventing expression of a truncated form of the E1B55K protein (Barker and Berk, 1987).

This is consistent with previous results from single-gene analyses and with enhanced expression of inhA associated with a mutation that generates an extended −10 consensus in drug-resistant strains of M. tuberculosis (Ramaswamy et al., 2003).

The Min (multiple intestinal neoplasias) allele of APC was induced by ethylnitrosourea (ENU), and carries a point mutation that generates a premature stop codon (see the following section for more details) [ 10, 11].