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Males carrying a mutation that eliminates GABA synthesis, unc-25, show decreased dorsal and ventral tail curling in response to increased levels of acetylcholine.
By analyzing mice with a Dido3-specific mutation that eliminates almost 50% of the Dido3 C-terminal sequence, we show that Dido3 is essential for early embryonic development.
Conversely, if a HisMBP-TEV-Sna3C with a K125A mutation that eliminates Sna3 ubiquitination but still retains its Rsp5-binding PPXY motif is used, Ub is ligated to both HisMBP and Rsp5WW1-3-HECT.
The dat-1 (ok157 )III strain was a gift of J. Duerr and J. Rand (Oklahoma Medical Research Foundation, Oklahoma City) and is a complete loss-of-function mutation that eliminates the majority of the DAT-1 coding sequence.
One of these introduces a premature stop codon into the third exon of gene mel-32 C05D11.11, and the other is a splice junction mutation that eliminates the splice donor site of first intron of the gene cki-2 T05A6.2.
We showed that a mutation that eliminates the CP 1 6 motor neurons does not significantly decrease aldicarb-induced ventral tail curling suggesting that there are cholinergic neurons that act, in part, in parallel to the CP motor neurons to regulate ventral tail curling.
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Only 7 out of the 12 populations studied showed changes in their genomic sequence, which included four reversions (17% of the changes), one mutation that eliminated a stop codon in nef coding region of virus H (Table 1) and a common mutation in the 5'LTR in three viruses, as described [4].
A new construct was designed encoding an engineered gelatin, FG-5009, with point mutations that eliminated the charge heterogeneity.
In addition, a defective transposable element family from Phytophthora infestans was named DodoPi as it contained mutations that eliminated the element's ability to jump to new locations in a chromosome.
Further, mutations that eliminate the microtubule-binding domain of APC result in defective chromosomal segregation [46].
It is possible to address CTCF function in intact animals using mutations that eliminate detectable CTCF protein.
More suggestions(15)
mutation that abrogates
mutation that chokes
mutation that produces
mutation that disrupts
mutation that interferes
mutation that closes
mutation that is
mutation that arises
mutation that lowers
mutation that helps
mutation that results
mutation that indicates
mutation that occurs
mutation that afflicts
mutation that creates
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