Sentence examples for mutation that decreased from inspiring English sources

Position 172 was also the only extracellular mutation that decreased surface expression.

In particular, we analyzed the effects of the D27L, E34F, R37A superclamp mutation that strongly inhibited cell cell fusion, and of a 'poor-clamp' mutation that decreased the clamping efficiency of CpxI (K26A).

The population diversity first suffers striking expansions in the presence of mutagens and then compressions either when the presence of the mutagenic analogue was discontinued or when a mutation that decreased sensitivity to a mutagen was selected.

While the specific functional consequence of each mutation remains to be assessed, each allele was a partial loss-of-function mutation that decreased cellular fitness and we selected alleles that showed hypomorphic growth with temperature-dependent phenotypes and low incidence of suppressors, gpn2 -2 and gpn3 -1, for further study.

A similar, albeit less pronounced, contraction would occur as a consequence of the dominance of viral mutants with decreased sensitivity to R. The MARLS-derived populations that replicated in the presence of R (the RA lineage, Figure 1B), showed unexpected high resistance to extinction at passage 35 and subsequent passages, associated with a mutation that decreased the sensitivity to R [ 40].

With these underlying influences, it is not clear what the effect of a mutation that decreases partially the sensitivity to a mutagenic agent would be regarding extinction.

Therefore, it is possible that a mutation that decreases expression of the B. anynana orthologue of ebony or increases expression of the yellow orthologue could produce the dl phenotype.

In the present report we have addressed this question by investigating whether a mutation that decreases sensitivity of FMDV to R can impede extinction of the virus in the course of cytolytic passages of the virus.

The less stable domains tend to form aggregates and any mutation that decreases domain stability could lead to AL [ 9].

Indeed, a mutation that increases the negative charge of the CpxI accessory helix inhibits release and a mutation that decreases the negative charge enhances release.

By comparison, the QTL on chromosome 6 at about 40 Mb (Table  7) appears to have arisen in B. indicus due to a mutation that decreases height and weight and now has an allele frequency of 0.1.