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The single mutation that creates Tamiflu resistance appears to be spontaneous, and not a reaction to overuse of the drug.
Researchers have identified a genetic mutation that creates incipient teeth in bird embryos.
In the HF1551 optical map, we observe a point mutation that creates a SwaI restriction site in the PARK2 gene.
The recessive allele (e) leads to the production of only pheomelanin because of a frameshift mutation that creates a prematurely terminated, non-functional receptor [ 2, 3].
One possible addition would be to include a rate of deleterious mutation that creates non-functional genes that do not contribute to fitness.
As control for the wild-type TP53 allele, four, and nine, WBCs from patients TRF001321 and TRF000155, respectively, were isolated and TP53 were sequenced; del, deletion; fs*13, frameshift mutation that creates a premature stop codon 13 aminoacids downstream.
Similar(53)
Can we determine whether recombination involving C3 preceded or followed the mutation that created A111T?
Strain QE14 also had the –11 C to T mutation that created the stronger –10 consensus sequence (TACAAT).
Tumor initiation and progression are dependent on rare, stochastic mutations that create genetic variability in a cell population.
But Greaves and colleagues suspected this process could go awry, introducing mutations that create flawed B cells that could cause leukemia.
The high-plasticity positions close to the original ("native") active-site are the most promising candidates for mutations that create a second active-site associated to a new function.
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mutation that arises
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Justyna Jupowicz-Kozak
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