Sentence examples for mutation that changed from inspiring English sources

The results showed the existence of a silent allele 13 in both families, due to a point mutation that changed guanine to adenine at 32 nucleotides downstream from the 3′ end of the AAGG repeat sequences in all four members.

To confirm that capt was the affected gene, we sequenced the capt locus from the punctate mutant and found a nonsense mutation that changed amino acid lysine 304 to a premature stop codon.

The M1326 line contained a base substitution of 977A to T, which resulted in a missense mutation that changed Asp326 (GAT) to Val (GTT).

We then evolved the deletion strain and observed that the genetic adaptation was recurrently based on a strategic mutation that changed the anticodon of other tRNA genes to match that of the deleted one.

To assess whether γH2A is important in the absence of CSN complex, we constructed a csn1Δ strain in which both histone H2A genes contained a mutation that changed the C-terminal SQE phosphorylation motif to AQE (hta1-S129A hta2-S128A), whish is the so-called htaAQ genotype.

For rescue experiments, a mutation that changed Gly 115 to Arg was made in the SpRunt-1 full length rescue clone [ 7] by the QuickChange® II Site-Directed Mutagenesis method (Stratagene), using the primers described above for the SpRunt-1 expression plasmid.

When a drug attacks a viral protein, the rapidly reproducing virus can develop a mutation that changes the protein in a manner that confers resistance to the drug.

"One in two genes carries a mutation that changes the protein it encodes".

Each mutant version of p53 contains a single point mutation that changes one amino acid in the p53 protein sequence.

This mutation is a non-synonymous mutation that changes the aminoacid residue 99 of the ND1 sub-unit from asparagine to serine.

Sequencing F32G8.6 exons from the original allele cat-4 (e1141 ), revealed a missense mutation that changes an amino acid (T66I) that is 100% conserved in GTPCH1 proteins.