Sentence examples for mutation tests were from inspiring English sources

KRAS and BRAF V600E mutation tests were performed in 762 primary tumors from a consecutive cohort study of Chinese CRC patients.

Of note, BRCA mutation tests were negative in all 10 patients screened in the University of Colorado cohort (27 cases), and in 22 out of 24 patients screened in the MD Anderson Cancer Center cohort.

Both KRAS (codons 12 and 13) and BRAF (p.V600E) mutation tests were performed using a multiplex allele-specific PCR-based assay (ACCB, Beijing, China), together with the Stratagene Mx3000P (Agilent Technologies Inc ,Santa Clara, CA), which assesses seven different potential mutations in KRAS codons 12 and 13 (Gly12Asp, Gly12Arg, Gly12Cys, Gly12Ser, Gly12Val, Gly12Vand and Gly13Asp).

The mutation tests were performed in the LightCycler 1.2 (p53) or LightCycler 480 (MDM2) instrument, using the FastStart DNA Master Hybridization Probes kit with 3 mM MgCl2 (Roche Diagnostics, Mannheim) in a total volume of 20 μl, and analyzing the melting curve of the hybridization probes releasing from the PCR product.

The number of cancer recessive genes in a simulation by random association of the four mutation tests was of 60.5 (false detection rate of 0.39).

As a consequence, several NGS-based workflows for clinical BRCA1 and BRCA2 mutation testing were recently proposed [ 10- 16].

MTHFR 677 C-T and MTHFR 1298 A-C mutation testing were performed using Hologic's Invader Assay from Third Wave Technologies (Madison, WI).

If data permitted, diagnostic test accuracy parameters were estimated according to previous tests, e.g., separate estimates of the test accuracy of BRAF V600E mutation testing were used depending on whether IHC or MSI was the preceding test.

Almost all KRAS mutations tests were performed in a single molecular biology facility.

Mutation testing is a powerful and flexible test technique.

For example, mutation testing was combined with ACO to generate a test-input space [30].