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The number of cancer recessive genes in a simulation by random association of the four mutation tests was of 60.5 (false detection rate of 0.39).
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KRAS and BRAF V600E mutation tests were performed in 762 primary tumors from a consecutive cohort study of Chinese CRC patients.
For example, mutation testing was combined with ACO to generate a test-input space [30].
To avoid possible interference of the code generation process with the results, we used three different programs versions generated from the models, on which the mutation testing was applied to assess the generated test sets.
The mutation test was performed on 1×107 copies of genomic DNA from blood cells (about 1 ml blood).
Informed consent for neuropsychometric and mutation testing was not requested as these are standard items of clinical care provided to DMD patients in the Sydney Neuromuscular Centre based on international benchmark standards of clinical practice.
In all families, TP53 mutation testing was negative [ 36].
In the 'B' families, mutation testing was first performed on an index affected individual.
The limit of detection for each mutation tested was 1% on the GS Junior (Roche).
Where available, information on BRCA1 and BRCA2 mutation testing was also taken into account.
APC gene mutation testing was reported in 222 patients [Table 1].
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