Interestingly, all regulatory gene SNVs were absent from P1M (using P1E as the reference), consistent with the appearance of the mutS mutation (Table S2).
In all, 4 of 13 cases had an early relapse and all of them harbored a CREBBP mutation (Table 1) whereas only 4 of 9 cases with a late relapse carried mutations (including the case that lost the initial mutation).
As a result, of the 22 haplogroups, 5 lineages harbored 2 pathogenic mutations while 6 lineages carried one potential pathogenic mutation (Table 3 and see networks of 4 major haplogroups in Fig. 2).
The number of clips attached to the bird's tip is changed by mutation following the mutation table (Fig. 3).
After DNA alteration, the student can determine the type of phenotype change caused by the mutation using a "mutation table".
Besides, ALK inhibitor therapy also could be tailored dependent on the variable types of mutation (Table 2) [13, 21 35].
In another example, LH-induced cyclic AMP production by LHR is abolished by the LHR A5936.59P mutation (Table 6).
We created the mutation table design to cause a larger shift of flight distance by a single mutation than in the original protocol.
After the DNA alteration, the students checked the type of phenotype change by mutation (here this means only base substitution) based on the "mutation table" (Fig. 3).
