Sentence examples for mutation suggesting the from inspiring English sources

However, aggregation properties of the mutant form were not influenced by the mutation, suggesting the SH3 domain forms amyloid via a non-cooperative process.

We found that H. salinarum NRC-1 has a low incidence of mutation suggesting the presence of active mechanisms to control spontaneous mutations during replication.

It is well known that large variations in cancer risks are also observed in families bearing the same mutation, suggesting the involvement of genetic and/or environmental modifiers.

High clonality LOH mutations were present when >75% of the DNA from the microdissected target had an LOH mutation, suggesting the presence of clonally expanded cells with that LOH mutation in the microdissected target.

We also observed a novel mutation at the same codon as the RNF213 founder mutation, suggesting the possibility that other missense mutations at this arginine position may be associated with MMD.

Remarkably, they were only found in rAML with an intact chromosome 2 and no Sfpi1 point mutation, suggesting the involvement of Flt3-ITD and Sfpi1 are mutually exclusive and which is in agreement with published data from the Danish tAML study (53).

Interestingly, a microarray analysis of RUNX1 mutation suggested the importance of miR-223 [ 39].

Almost all elements analyzed carried numerous mutations suggesting the presence of a RIP-like mechanism in M. graminicola.

The oligomerisation of Irga6 was not prevented by numerous other mutations, suggesting the absence of a second well-defined surface interface contributing to oligomerisation.

A substantial proportion of patients with IM resistance do not have BCR-ABL tyrosine kinase domain mutations, suggesting the involvement of additional mechanisms in IM resistance.

Basal-like tumors showed a high frequency of TP53 mutations, suggesting the loss of TP53 function occurs within most of basal-like cancers [ 5].