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Coadministration with GDC-0973 resulted in significant decreases in 18 F-FDG uptake across almost all cell lines, independent of mutation status; the combination treatment strikingly overcame the A375R1 and R3 cell lines lack of response to vemurafenib alone.
Regardless of the mutation status, the severity of HoFH is based on LDL-C levels [ 6].
Regardless of KRAS mutation status, the addition of panitumumab resulted in inferior PFS compared to control.
Although we did not discern a relationship to gene mutation status, the overall frequency of TP53 gene mutation was relatively low.
(C ) ROC curves for the three predictive models under comparison, i.e., the p53 mutation status, the 215-feature and the 13-gene signature models.
Immunohistochemistry (IHC) established p16 expression and EGFRvIII mutation status; the latter was also determined using quantitative reverse transcription polymerase chain reaction as previously described [ 19].
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We profiled the mutation status of the PIK3Ca gene in the National Cancer Institute (NCI -60 paNCI -60human cancer cell lines maintained by the Developanelal Therapeutics Profram of thumanI.
The mutation status of the ras oncogenes in the AML cell lines are also shown.
The mutation status of the KRAS gene affects the response of cetuximab.
Interaction was present between the mutation status and the number of births and between the mutation status and the total duration of breast feeding (P = 0.007 and P = 0.045, respectively).
First, we could not compare the results of the EGFR mutation status in the pleural effusion fluid to the mutation status in tumour tissue.
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