Sentence examples for mutation status rather from inspiring English sources

In the present study, we assessed MUC5B as a biomarker for NSCLC based on EGFR mutation status rather than on all NSCLCs, identifying MUC5B as a favourable prognosis biomarker for EGFR mutant NSCLC.

Although we found that the selected texture features significantly improved our ability to distinguish between mutation carriers and non-carriers when compared with PMD alone, ours was a cross-sectional study evaluating features associated with BRCA1/2 mutation status rather than subsequent risk of developing breast cancer.

Even though the design of this study differed from ours in that the erlotinib administration schedule was daily rather than intermittent, and that collection of EGFR mutation status data was discretionary rather than mandatory, the significant survival benefit brought about by this combination therapy has encouraged us to continue our ongoing phase II study until we have overall survival data.

The authors concluded that the adverse prognosis for BRCA2 mutation carriers seems to depend on the presence of more adverse tumor characteristics at diagnosis rather than mutation status per se [ 22].

Our finding of resistance to targeted agents in the presence of FGFR3 mutation underscores the need to use biomarkers of FGFR dependence rather than mutation status when selecting patients for therapy in the future.

In conclusion, the poor prognosis of young BRCA1/2 mutation carriers with breast cancer is mainly explained by the prevalent occurrence of negative prognostic factors rather than mutation status per se, and can to at least some extent be abrogated by the use of chemotherapy.

The extent of CHD risk conferred by these factors is of such magnitude that the genetic predisposition associated with HFE carrier status is rapidly outweighed as seen in Table  4 where it is shown that greater CHD risk is associated with smoking status rather than with HFE mutations.

In fact, our mutational analysis demonstrated that loss of PTEN expression was not associated with PTEN mutational status, but rather with the presence of frameshift or non-sense mutations that produce truncated PTEN proteins (Table 6).

Initial studies investigating the effect of BRCA mutation status on PR expression in non-malignant cells did not distinguish by isoform, but rather focused on determining total PR protein levels.

If D.I. is really about status rather than fairness, could A.I. be about status, too?

"No," he agrees, "it's about status rather than class.