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And at the relapse, two cell populations of the different affinity for rituximab has arose ('R-high' and 'R-low'), and both had a genome of the same mutation status, however, the expression of the mutated mRNA has been predominant only in 'R-low'.
We did not find any significant association between smooth borders and discordant mutation status, or irregular borders and concordant mutation status, however.
We observed clustering within CLL according to IGVH mutation status; however, both types of CLL were more similar to memory B cells than naive at these 4752 sites.
Similar(57)
Only limited information on first course of treatment was available and it is possible that treatment could have differed according to KRAS-mutation status; however, 95% of cases were diagnosed before 2006 at a time before KRAS-mutation status might have been used to decide on anti-EGFR therapy.
However, mutation status has been studied in particular as a predictive marker in the first line use of EGFR inhibitors.
Unfortunately, however, the mutation status or phenotype was not known for all family members.
However, TP53 mutation status had no significant influence on disease-free survival when this group was analysed separately.
Currently, however, the mutation status of the epidermal growth factor receptor (EGFR) and the arrangement status of anaplastic lymph kinase (ALK) are independent pathologic types in NSCLC.
Based on these results, we reviewed the EGFR mutation status of lung cancer specimens, however, we did not have complete EGFR mutation data because our sample set included early records from when EGFR mutation detection was not routine clinical practice.
However, whether KDM6A mutation status holds significant prognostic value in cancer is yet to be determined.
The BRCA1 mutation status of Campbell's subjects was however not reported.
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