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However, whether KDM6A mutation status holds significant prognostic value in cancer is yet to be determined.
However, this study indicates that timely molecular characterisation of the disease is important and that plasma KRAS mutation status holds important predictive and prognostic information regarding the outcome of irinotecan monotherapy in mCRC, whereas the use of archival tumour tissue seems insufficient.
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This lack of association between pathological response and mutation status held true for both ER-positive and ER-negative tumors.
Mrs. Quaid insisted the car's status holds no appeal.
Additionally, many people who do know they have such a mutation can now take preventive measures (such as Angelina Jolie's recent pre-emptive double mastectomy upon learning her BRCA gene mutation status), and we have no way of knowing whether they would have gone on to develop cancer if these measures had not been taken.
Neither mutation status nor miRNA expression improved the estimated prediction.
Prognostic factors examined included baseline TLG, RAS mutation status, FDG heterogeneity and dose heterogeneity.
No significant correlation was found between baseline TLG or RAS mutation status and response.
Therefore, the authors concluded that KRAS mutation status was not a predictive factor for chemotherapy [19].
Two hundred colorectal cancers from FFPE tissue previously characterized for KRAS mutation status were evaluated for PIK3CA mutations.
Other features that correlate with IDH mutation status include normal karyotype, intermediate-risk cytogenetics, NPM1 mutation, and M1 AML subtype (Chou et al., 2010; Schnittger et al., 2010).
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