Sentence examples for mutation status has from inspiring English sources

More recently, a mutated Kras-specific signature that can be used to classify human and mouse lung tumours on the basis of their KRAS mutation status has been identified by comparing KRAS-mutated human cancer cells to mouse somatic cells containing knocked-in mutant Kras [275].

KRAS mutation status has been reported to be a predictive marker of tumor response to epidermal growth factor receptor (EGFR) inhibitors.

TP53 mutation status has been shown to be one of the strongest single molecular prognostic markers in breast cancer.

The RPS19 mutation status has not been predictive of response in any series.

For all tumor samples the mtDNA mutation status has been previously determined [ 7].

In addition, BRCA2 mutation status has been confirmed as an independent prognostic factor for poorer outcome [7].

Gene expression, miRNA expression, ER status, HER2 status and TP53 mutation status have been described before (Enerly et al, 2011).

However, TP53 mutation status had no significant influence on disease-free survival when this group was analysed separately.

Recently, MMR status, KRAS and BRAF mutation status have attracted remarkable attention due to their potential prognostic and predictive role in colorectal carcinomas [ 10- 12].

This finding is unlikely to be due to sequencing inconsistencies, as the methods employed to determine BRAF and KRAS mutation status had been intensively validated [ 28, 38, 39].

Epithelial growth factor receptor (EGFR) and KRAS mutation status have been reported as predictive markers of tumour response to EGFR inhibitors.