Occasionally, a mutation is an improvement that makes the molecule more likely to reproduce, and the mutation spreads throughout the population.
Four years ago, researchers thought that they would find hundreds of examples in which an advantageous mutation spread rapidly in a particular population.
2) This mutation spread through the focal population between generations 500 and 1500.
This mutation spread through its population of origin between 500 and 1500 generations.
This pattern suggests that the arrays are subject to homogenisation – so that novel variants arising by mutation spread relatively rapidly along the array within any one species [ 2- 4].
The mutation spread in its source population between generation 500, when it was rare or absent, and generation 1500, when it was present in almost every cell.
In one of the epitopes studied (gene nef in patient CH40), a mutation spread sufficiently slowly such that it was possible to observe the mutation rise from low frequency at day 16 to high frequency at day 45.
Over evolutionary time, such a mutation spreads in two dimensions: horizontally among TE-derived regulatory elements and vertically through the population, until it is fixed across elements and across individuals.
Over 40 different mutations spreading over both domains of Gne can cause HIBM.
This high-coverage metagenomics analysis identified a large number of mutations spreading in glucose-limited populations.
